(一)科研项目: 1. 国家自然科学基金面上项目,PCV2诱导的猪内皮源IL-8调控单核细胞源树突状细胞分化及其信号机制(31472174),主持(2015-2018) 2. 北京市自然科学基金-北京市教育委员会科技计划重点项目,PCV2感染猪肠道黏膜免疫功能变化及其对肠道菌群影响(KZ201510020022),主持(2015-2017) 3. 北京市自然科学基金委员会-北京市教育委员会科技计划重点项目,PCV2感染的猪肠上皮细胞调控T细胞分化的分子机制(KZ201910020021),主持(2019-2021) 4. 国家自然科学基金面上项目,PCV2感染猪血管内皮细胞在血源树突状细胞分化与致免疫耐受中作用(31272571),主持(2013)
(二)代表论文: 1. Yuanyuan Chu, Yuheng He, Wenzhu Zhai, Ying Huang, Chunhao Tao, Zhongbao Pang, Zhen Wang, Dekun Zhang, Huanrong Li, Hong Jia. 2024, CpG adjuvant enhances humoral and cellular immunity against OVA in different degrees in BALB/c, C57BL/6J, and C57BL/6N mice. Int Immunopharmacol. 10(138): 112593. 2. Mengyu Zhang, Weicheng Xu, Ning Yang, Zhuowei Li, Shuanghai Zhou, Xuewei Liu, Jianfang Wang, Huanrong Li. 2024, PCV2 induced endothelial derived IL-8 affects MoDCs maturation mainly via NF-κB signaling pathway. Viruses, 16(4): 646. 3. Cheng Han, Weicheng Xu, Jianfang Wang, Xiaolin Hou, Shuanghai Zhou, Qinye Song, Xuewei Liu, Huanrong Li. 2023, Porcine circovirus 2 increases the frequency of transforming growth factor-β via the C35, S36 and V39 amino acids of the ORF4, Viruses, 15(7): 1602 4. Zhanning Shen, Bo Liu, Zhen Zhu, Jige Du, Zhiyu Zhou, Chenfan Pan, Yong Chen, Chunsheng Yin, Yufeng Luo, HUanrong Li, Xiaoyun Chen. 2023, Construction of a triple-gene deletion mutant of Orf virus and evaluation of its safety, Immunogenicity and Protective Efficacy, Vaccines, 11(5): 909 5. Xuewei Liu, Yang Wang, Cheng Han, Qiuming Li, Xiaolin Hou, Qinye Song, Shuanghai Zhou, Huanrong Li. 2022, TGF-β from the porcine intestinal cell line IPEC-J2 induced by porcine circovirus 2 increases the frequency of Treg cells via the activation of ERK (in CD4+ T Cells) and NF-κB (in IPEC-J2). Viruses. 14(11): 2466.
(三)授权专利 1.一种肉类成分四重PCR的检测方法与应用。李焕荣,盖新娜,等,第一完成人。 |