(一)科研项目: 1. 国家自然科学基金面上项目,黄芪多糖对PRRSV感染PAMs致肺MVECs功能障碍的调控作用及其机制研究,主持(2023-2026) 2. 国家自然科学基金面上项目,PRRSV对猪肺微血管内皮细胞功能的影响及对其调控性中药成分的筛选,主持(2017-2020) 3.国家自然科学基金青年科学基金项目,中药多糖对内皮糖萼影响及与其免疫调节作用的相关性研究,主持(2011-2013) 4.北京市自然科学基金面上项目,甘草次酸对PRRSV感染致猪肺MVECs损伤的调控作用研究,主持(2024-2026) 5.北京市自然科学基金面上项目,PRRSV感染对LPS致猪肺MVEC炎性反应的影响及调控性中药成分的筛选,主持(2020-2022) (二)代表论文: 1. Xinyue Yao, Wanwan Dai, Siyu Yang, Zhaoli Wang, Qian Zhang, Qinghui Meng, Tao Zhang*. 2023, Synergistic effect of treatment with highly pathogenic porcine reproductive and respiratory syndrome virus and lipopolysaccharide on the inflammatory response of porcine pulmonary microvascular endothelial cells, Viruses. 15(7): 1523. 2. Yanmei Wu, Xiaoxiao Song, Peishan Li, Zhaoli Wang, Zhanzhong Zhao, Tao Zhang*. 2023, Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules, Int. Immunopharmacol. 118: 110012. 3. Xiaoxiao Song, Yanmei Wu, Xianping Wu, Ge Hu, Tao Zhang T*. 2022, Effects of highly pathogenic porcine reproductive and respiratory syndrome virus infection on the surface glycoprofiling of porcine pulmonary microvascular endothelial cells, Viruses. 14(11): 2569. 4. Yanmei Wu, Xiaoxiao Song, Defeng Cui, Tao Zhang*. 2022, IFIT3 and IFIT5 play potential roles in innate immune response of porcine pulmonary microvascular endothelial cells to highly pathogenic porcine reproductive and respiratory syndrome virus, Viruses. 14(9): 1919. 5. Yanmei Wu, Zhaoli Wang, Ge Hu, Tao Zhang*. 2022, Isolation and culture of rat intestinal mucosal microvascular endothelial cells using immunomagnetic beads, J. Immunol. Methods. 507: 113296. 6. Tao Zhang*, Chun Liu, Ge Hu, Hong Dong, Xiang Mu. 2020, Synchronous vasomotion of skin microvessels at acupoints on the twelve main meridians of beagle dogs, Skin. Res. Technol. 26(6): 851-858. 7. Peishan Li, Zhongjin Yang, Shun Ma, Ge Hu, Hong Dong, Tao Zhang*. 2020, Susceptibility of porcine pulmonary microvascular endothelial cells to porcine reproductive and respiratory syndrome virus, J. Vet. Med. Sci. 82(9): 1404-1409. 8. Bo Feng, Qian Zhang, Jianfang Wang, Hong Dong, Xiang Mu, Ge Hu, Tao Zhang*. 2018, IFIT1 expression patterns induced by H9N2 virus and inactivated viral particle in human umbilical vein endothelial cells and bronchus epithelial cells, Mol. Cells. 41(4): 271-281. 9. Xiong Sun, Zhongjin Yang, Hong Dong, Xiang Mu, Tao Zhang*. 2015, A randomized, controlled study of the effects of Hong Hua (Carthamus) extracts on skin microvascular vasomotion at acupoint Pi-shu and on NO and ET-1 production from microvascular endothelial cells in a murine model, Am. J. Tradit. Chin. Vet. Med. 10(1): 25-29. 10. Tao Zhang*, Shuang Wu, Xiong Sun, Huiqin Duan, Xiang Mu. 2014, Effects of polysaccharides from pulsatilla decoction on the microvascular endothelial glycocalyx, J. Integr. Agr. 13(11): 2558-2561. (三)代表著作 1.国家级优秀教材-动物解剖学与组织胚胎学(第二版).高等教育出版社,2017.1 2.国家级规划教材-彩图动物组织学与胚胎学实验指导(第三版).中国农业大学出版社,2022.4 3.教育部“一村一名大学生计划”教材-家畜解剖基础(第二版)国家开放大学出版社,2024.1 4.教育部“一村一名大学生计划”教材-兽医基础.国家开放大学出版社,2022.7 5.教育部“一村一名大学生计划”教材-动物常见病防治.国家开放大学出版社,2022.1 (四)授权专利 1.治疗猪繁殖与呼吸综合征的中药方剂及其制备方法(ZL202010973918.X),张涛,陈武,穆祥,王祥芹,胡格,董虹,第一完成人。 2.黄芪多糖在提高乳杆菌黏附肠道上皮细胞能力中的应用(ZL202110201647.0),张涛,王安如,穆祥,任晓明,张永红,胡格,第一完成人。 3.一种可调大小兽用开口器(ZL202123069115.0),张涛,宋胜,李晋珍,胡格,第一完成人。 4.一种免疫细胞化学染色盒(ZL202220333689.X),张涛,吴艳梅,胡格,董虹,第一完成人。 5.阿司匹林用于制备穴位激活剂的用途(ZL2015101350346)穆祥,张涛,段慧琴,胡格,董虹,姜代勋,张倩,第二完成人。 6.口蹄疫疫苗免疫增强剂(ZL200910080015.2),穆祥,张涛,索占伟,胡格,段慧琴,董虹,张涛,徐巨,王淑荣,许冠英,第二完成人。 7.一种口蹄疫疫苗免疫增强剂(ZL200910080016.7),穆祥,张涛,胡格,索占伟,段慧琴,董虹,张涛,徐巨,袁希民,王庆波,第二完成人。 8.一种非治疗用提高微血管自律运动振幅中药成分筛选方法(ZL200910080017.1),穆祥,索占伟,张涛,段慧琴,陈武,胡格,董虹,第三完成人。 |